CST Blog Microglia Activation Antibody Toolkit to Study TREM2 Signaling

Selecting antibodies for molecular signaling research in neurodegeneration is a complex and nuanced process, yet it is essential for advancing our understanding of brain function and disease. This blog explores a collaborative project between CST and FUJIFILM Cellular Dynamics, where we used iCell Microglia products alongside a toolkit of key antibodies to characterize signaling events in neurodegenerative diseases. The antibodies we selected provide a valuable, high-content method for verifying the identity and functionality of iPSC-derived microglia (iMGL), particularly in the context of neuroinflammation.