NeuroNascent: Neuronascent to Present Further NNI-362 Phase1a Data at CTAD 2022 for Alzheimer's Disease

ROCKVILLE, Md., Nov. 08, 2022 (GLOBE NEWSWIRE) -- Neuronascent Inc., today announced its abstract entitled "Reduction of plasma p-Tau181 from a Phase 1a Randomized Trial of NNI-362 in a healthy aged population consistent with amelioration of tau hyperphosphorylation in human differentiated neuron cultures" has been accepted for a poster presentation at 15th Clinical Trials on Alzheimer's Disease (CTAD 2022) to be held in San Francisco, Calif., on Nov. 29 through Dec. 2, 2022. The primary goal of this trial was to assess the safety and tolerability of oral NNI-362 in healthy aged subjects. "These findings are very encouraging since the pre-clinical results are indeed being mimicked in the clinic, including both safety and potential efficacy markers, as we move toward a Phase 2 proof-of-concept trial," said founder and CEO Judith Kelleher-Andersson, PhD. Dr. R. Scott Turner, MD, PhD, director of the Memory Disorders Program, Georgetown University, will be presenting this data at CTAD 2022 as one of the accepted late-breaking posters. The Phase 1a single ascending and multiple ascending dose (SAD + MAD) trial of NNI-362 demonstrated a significant reduction from pretreatment-baseline of an Alzheimer's disease progression biomarker, with no change observed ...Full story available on Benzinga.com