Twist Bioscience: Twist Bioscience Launches Flexprep Ultra-High Throughput Library Preparation Kit for Applications in Agrigenomics and Population Genomics

Twist Bioscience Corporation announced the launch of the FlexPrep Ultra-High Throughput Library Preparation Kit, designed with a proprietary Twist-developed enzyme to enable throughput at a low cost, and accelerate the adoption of NGS by microarray users in population and agricultural genomics (agrigenomics). Advanced sequencing technologies continue to drive increased sample volumes across multiple applications. The desire to profile tens of thousands to millions of samples in parallel, beyond just single nucleotide poly morphisms (SNPs), requires a next-generation sequencing (NGS) solution that enables high throughput applications at a reasonable cost. The Twist FlexPrep UHT Library Prep kit improves upon standard enzymatic fermentation library preparation methods with the introduction of a novel Normalization by Ligation? (NBL) technology, which eliminates the need for time-consuming upfront sample quantitation, and enables sample pooling and multiplexing early in the workflow. This built-in normalization and multiplexing capability simplifies how researchers prepare samples with variable mass at scale, where efficiency in workflow and per-sample cost is critical for NGS implementation. With the Twist FlexPrep UHT kit, researchers can run up to 1,152 samples in a single 96-well plate sequencing run, which can save researchers time and costs. Gencove is also collaborating with Gencove, a leader in low-pass genome sequencing methods and analysis software, to offer analysis solutions to customers using FlexPrep UHT to understand their data and deliver fast, cost-effective and accurate genotyping results. Gencove works in a partnership model to design custom assays, optimize sequencing solutions, and build analysis pipelines to effectively bridge the gap from samples to solutions in the fields of agriculture and human health. As compared to Twist Library Preparation EF Kit 2.0.