Clinical trials continue to evolve and so does the methodologies used to support and provide the vital clinical trial monitoring necessary to monitor and protect patient safety. The methods, techniques, and strategies used in our field change with the technology at hand, new regulations, and other challenges that may be present. In 2020, the biggest influence on the way our industry operates has been COVID-19. While the pandemic has limited the industry’s ability to access our investigative sites and perform onsite monitoring, the coronavirus has expedited the rise and use of – remote monitoring and centralized monitoring.